Head Coach: Elmer W. Weber (22-18-5, 5th year)
Record: 2-5-2 (2-2 Tiny Ten, 0-2 City)
Results
* – denotes Tiny Ten Conference contest
| Date | Opponent | Score | Comment |
| Sep. 28 | @ Grayville (Ill.) | T 0-0 | |
| Oct. 5 | @ Boonville * | W 32-12 | |
| Oct. 12 | Madisonville (Ky.) | L 7-14 | |
| Oct. 19 | New Albany | T 13-13 | |
| Oct. 26 | @ Mount Carmel (Ill.) * | W 13-12 | |
| Nov. 2 | Kentucky Military Academy | L 6-13 | |
| Nov. 9 | Owensboro (Ky.) | L 6-60 | |
| Nov. 16 | Bosse * | L 0-6 | |
| Nov. 23 | @ Providence (Ky.) | N/A | Cancelled by Providence |
| Nov. 28 | @ Central * | L 6-12 | Thanksgiving |
Individual Honors
- Acker
- All-Tiny Ten honorable mention end
- Frank Angle
- All-Tiny Ten third team halfback
- Sunday Courier & Journal halfback
- Press All-City halfback
- Charlie Fischer
- All-Tiny Ten center
- Sunday Courier & Journal center
- Press All-City center
- Millard Fisher
- All-Tiny Ten honorable mention tackle
- Press All-City guard
- Hickrod
- All-Tiny Ten honorable mention guard
- Press All-City second team guard
- Carl Thielman
- All-Tiny Ten honorable mention fullback
- Press All-City honorable mention fullback
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