Head Coach: Herman Byers (47-12-4, 7th year)
Record: 10-0 (4-0 SIAC Large, 3-0 City)
Ranking: #1 in final Litkenhous Ratings & final UP Rankings; also, a cross-section of sportswriters and coaches picked Reitz as “Indiana’s best grid team”
Championships: State, SIAC & City Champs
Results
* – denotes SIAC Large School Division contest
| Date | Opponent | Score | Comment |
| Sep. 10 | @ Henderson Barrett (Ky.) | W 38-6 | |
| Sep. 17 | St. Louis Central (Mo.) | W 45-0 | |
| Sep. 24 | @ Muncie Central | W 41-6 | |
| Oct. 1 | East Chicago Roosevelt | W 32-6 | Roughriders’ first loss since 1944 featured in Legendary Game Series |
| Oct. 8 | Central * | W 47-14 | |
| Oct. 15 | @ Indpls. Washington | W 38-13 | |
| Oct. 30 | @ Hammond | W 41-6 | |
| Nov. 5 | Bosse * | W 18-0 | |
| Nov. 11 | Bloomington * | W 39-0 | Armistice Day |
| Nov. 25 | Memorial * | W 14-0 | Thanksgiving |
Individual Honors
- Malcolm Cook
- AP All-State end
- Clark All-State right end
- Indianapolis News All-State end
- UP All-State end
- All-SIAC end
- Evansville Downtown Quarterback Club All-City end
- Sunday Courier & Press All-City end
- Erwin Deig
- Evansville Downtown Quarterback Club All-City guard
- Pete Fisher *
- AP All-State back
- Clark All-State quarterback
- Indianapolis News All-State back
- UP All-State back
- All-SIAC back
- Evansville Downtown Quarterback Club All-City quarterback
- Sunday Courier & Press All-City quarterback
- Don Folz
- All-State (unknown selector)
- Clark All-State second team right guard
- All-SIAC honorable mention guard
- Sunday Courier & Press All-City guard
- Bob Hertzberger
- AP All-State end
- Clark All-State second team left end
- Indianapolis News All-State second team end
- UP All-State second team end
- All-SIAC end
- Evansville Downtown Quarterback Club All-City end
- Sunday Courier & Press All-City end
- Harold McMillen
- AP All-State honorable mention tackle
- All-SIAC honorable mention tackle
- Earl Morris
- All-SIAC honorable mention guard
- Don Steinmetz
- All-SIAC honorable mention center
- Robert Yokel
- All-SIAC tackle
- Sunday Courier & Press All-City tackle
- Tom Wilson
- Indianapolis News All-State back
- UP All-State second team back
- AP All-State honorable mention back
- All-SIAC back
- Evansville Downtown Quarterback Club All-City halfback
- Sunday Courier & Press All-City halfback
Team Honors
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