Head Coach: Herman Byers (53-15-4, 8th year)
Record: 6-3 (3-1 SIAC Large, 2-1 City)
Ranking: #2 in final Litkenhous Ratings & UP Rankings
Championships: SIAC & City Champs
Results
* – denotes SIAC Large School Division contest
| Date | Opponent | Score | Comment |
| Sep. 15 | Henderson Barrett (Ky.) | W 40-0 | |
| Sep. 24 | Muncie Central | W 28-6 | |
| Sep. 30 | @ East Chicago Roosevelt | L 12-20 | |
| Oct. 7 | Central * | W 26-0 | |
| Oct. 14 | @ Bloomington * | W 21-6 | |
| Oct. 21 | Hammond | W 18-7 | |
| Nov. 4 | Bosse * | W 27-12 | |
| Nov. 11 | @ South Bend Riley | N/A | cancelled after Riley qualified for NIHSC title game |
| Nov. 11 | @ South Bend Central | L 20-21 | |
| Nov. 19 | Memorial * | L 6-7 |
Individual Honors
- Phil Byers
- UP All-State honorable mention halfback
- Jim Dunn
- Evansville Downtown Quarterback Club All-City tackle
- Pete Fisher
- AP All-State quarterback
- Clark All-State quarterback
- Indianapolis News All-State back
- All-SIAC Large School Division back
- Sunday Courier & Press All-City quarterback
- Evansville Downtown Quarterback Club All-City quarterback
- Don Henry
- All-SIAC Large School Division honorable mention end
- Harold McMillen
- AP All-State third team tackle
- Clark All-State second team left tackle
- Indianapolis News All-State second team tackle
- UP All-State second team tackle
- All-SIAC Large School Division tackle
- Sunday Courier & Press All-City tackle
- Merle Reed
- All-SIAC Large School Division honorable mention end
- Evansville Downtown Quarterback Club All-City end
- Don Steinmetz
- UP All-State center
- AP All-State honorable mention center
- Indianapolis News All-State third team center
- All-SIAC Large School Division honorable mention center
- Sunday Courier & Press All-City center
- Evansville Downtown Quarterback Club All-City center
- Byron Watson
- All-SIAC Large School Division honorable mention guard
- Tom Wilson
- UP All-State fullback
- AP All-State third team halfback
- Clark All-State fourth team fullback
- All-SIAC Large School Division back
- Sunday Courier & Press All-City halfback
- Evansville Downtown Quarterback Club All-City halfback
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